Increases in body mass index (BMI) increase the risk of several types of cancer, common and less common, according to a study by the University of Manchester the Christie Hospital NHS Foundation Trust 'in Manchester (UK) published in the journal' The Lancet '.
This increased risk varies between the sexes and different ethnic groups depending on the type of cancer. Researchers conducted an analysis of previous studies of 221 datasets incorporating 282,137 cases to determine the cancer risk associated with a 5 kg/m2 increase in BMI.
The authors found that in men, a 5 kg/m2 increase in BMI stood the risk of esophageal cancer by 52 percent, thyroid by 33 percent, and colon and kidney by 24 percent .
For women, the same increase in BMI increased the risk of endometrial and bladder cancers by 59 percent, esophagus by 51 percent and kidney by 34 percent.
Other weaker associations showed an increase in rectal cancers and melanoma in men: breast, pancreatic, thyroid and colon cancer in women, and leukemia, multiple myeloma and non-Hodgkin lymphoma in both sexes.
The scientists also found that the associations were stronger in men than in women in the case of colon cancer, 24 versus 9 percent increase in risk. The associations were similar in studies from North America, Europe and Australia, and in the Asia-Pacific region but found a link between the even greater increase in BMI and breast cancers in the populations of the latter region.
The authors conclude that these data support the study of biological mechanisms linking obesity to cancer.
http://www.azprensa.com
Triglycerides Linked to Coronary Disease Risk
study says should be taken into account along with LDL cholesterol in prevention efforts. By Ed Edelson HealthDay Reporter (SOURCES: Michael Miller, MD, director, preventive cardiology, University of Maryland Medical Center, Baltimore, Leslie Cho, MD, interventional Cardiologist, and Director, Women's Cardiovascular Center, Cleveland Clinic, Feb. 12, 2008 , Journal of the American College of Cardiology)
TUESDAY Feb. 12 (HealthDay News / Dr. HealthDay News) - A new study finds that high levels of triglycerides are strong predictors of heart problems and that, therefore, should be among the measures of blood fats programs prevention.
"Historically, triglycerides have been considered as second class citizens," said Dr. Michael Miller, director of preventive cardiology at the Medical Center of the University of Maryland and author of the report in the February 15 edition of the Journal of the American College of Cardiology ..
"LDL cholesterol has always been the center of attention. We know that LDL is closely related to bringing cholesterol to scavenger cells, which in turn deposited to form plaques in arteries. This study shows that triglycerides themselves are also lipids to blame. "
The original study was designed to evaluate the effectiveness of LDL-lowering statins, Pravachol and Lipitor, in reducing the recurrence of coronary disease after a heart attack. The new study examined data from 4.162 participants in the trial to observe the relationship between triglyceride levels and the incidence of heart problems and death.
"Patients who had heart attacks came back at 30 days, "said Miller." measured their levels of LDL and triglycerides, then gave them up over the next two years, to assess the occurrence of new events and death. If a patient had triglyceride levels below 150 [milligrams per deciliter], there was a 27 percent lower risk of having a new event with time.
After adjusting multiple variables such as age, diabetes, hypertension and obesity, the reduction in risk was twenty percent. "Unlike LDL cholesterol, for which the recommended level in blood is 70 or less there is no recommended level of triglycerides in blood, said Miller, but 150 milligrams per deciliter or below is "considered as desirable."
When participants were divided into four groups according to their levels of LDL and triglycerides, which were in the group who had triglyceride levels below 150 and LDL below 70 did better because their risk was 28 percent lower than the group with the highest reading of triglycerides and LDL.
Obviously, the results need to be confirmed, said Miller. "So far, we have a recommendation for triglyceride lowering, so the next logical step is a study to determine whether lowering triglycerides and LDL further reduced reduce the risk LDL alone, "he said.
are underway two studies that pursue this goal, Miller noted. Previous research had indicated that connection, a study published in the journal Neurology last December found a link between triglycerides and stroke risk, while research published in the Journal of the American Medical Association in July last year showed that having high levels of triglycerides in non-fasting cholesterol test involved a greater risk of heart attack in the future.
Dr. Leslie Cho, an interventional cardiologist and director of cardiovascular of women at the Cleveland Clinic, said that the new report "is not a big surprise." "All of this study is that even when you control bad LDL cholesterol below 70, still have to monitor triglycerides," Cho said.
triglycerides The problem is that "fat is the most unstable of the body, so it takes at least two readings to get an accurate measurement of blood levels, he said. For now, Miller said, "I am proactive about both LDL and triglycerides."
can take several steps to reduce triglyceride levels, many of which are already recommended on general principle to reduce coronary risk. One is to eat a Mediterranean diet rich in fish. The omega-3 fatty acids can reduce triglyceride levels, as well as niacin, and exercise has a beneficial effect, Miller said.
Statins also have a lowering effect on triglyceride levels, he noted. "If you can effectively reduce both LDL cholesterol and triglycerides, achieved a better result," said Miller.
http://healthfinder.gov
nutritivoysaludable@gmail.com 
0 comments:
Post a Comment